Without more information on the files in question it's hard to make a guess. There's an action in Reaper to analyse an item and give detailed info on Peak, RMS, LUFS, crest etc.
Given that your interface & its ASIO driver are out of the equation: Windows onboard audio driver problem, codec problem, unsupported bit depth/sample rate, auto enhancement options (either Windows control panel or Media Player options)come to mind.
Do you render out something like 192k and then probably Media Player forces down sampling or something like that?
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