I just bought the Nektar Impact 49+. I believe both of our keyboards only advertise "out-of-the-box" support for Reaper on Windows and OSX via Nektar DAW (Linux can still receive the raw MIDI).
HOWEVER, I was able to get the full integration to work on my Linux set up. I run the x64 version of Reaper on Wine64 on Ubuntu 16.04. I followed the "out-of-the-box" instructions Nektar provides for Windows. I registered with Nektar, downloaded the Nektar DAW installer for Windows 10, and ran it via wine64. Then followed the provided manual's instructions for configuring the MIDI and control through Reaper. Reaper was able to detect my Impact 49+, and just like that I had full MIDI support PLUS Play/Rewind/Loop support PLUS mixer channel volume adjustment support, etc.
I hope this info is useful you to, happy to help you get your keyboard working if you want to run Reaper via Wine.
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