The MOTU website says:
Quote:
The 8pre provides eight microphone/instrument preamps
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So as far as hardware/electrical connections you're ready to go! Except of course, you'll need some adapters for the XLR connectors on the other side of the wall, and you
may a TS/TRS plug to get high impedance into the 8pre. (Check the user manual or just try it to see if a straight guitar plug sounds different from an XLR connection.)
For guitars you may want to use amp/cabinet sims, but that's an artistic choice.