I've no experience with these, but I've read the SOS review of the Alesis Multimix 16 Firewire. They were pretty positive about it (given the low price of course). Cons: the preamps were a little noisy at highest gain settings, the mid EQ is a bit harsh for boosting. And the onboard effects are not very high quality...
There is a Multimix 8 (Firewire or USB) available... you might want to check that out.
Eddy
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