I found a thread from 2011 stating the limit on the number of different layouts was 20 at the time.
https://forum.cockos.com/showthread.php?t=89312
In a personal edit of Commala 5 I did last year, I believe I reached the same conclusion (colored faders add up!). However, my theming and WALTER “skills” could have been in question as well.
Does the 20 layout limit still exist? Thanks!