I haven't solved this issue yet, but have found a work-around.
After doing a portable-install elsewhere on my computer, if I start up and then try opening reaper via-the portable installed exe, reaper works. Then if I go and open it on the main install, it also works. But, if I come back later on after shutting down the computer, I sometimes still go back to the blue screen of death if I go straight for the normal exe without running the portable exe first.
Weird.
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