First off, what's your audio interface? And what Macbook Pro exactly? A new one with the T2 processor?
It could be a number of issues.
If you have a T2 security chip, it's connected via an Apple developed USB bridge. That bridge also connects keyboard, camera, internal audio and a number of other things. If this is the problem, you'll have to wait for Apple to maybe fix it. The best lie I heard, was that Apple didn't develop this chip for audio. Could be, as even internal audio shows problems sometimes. But it would be a very major oversight, wouldn't it?
Another possible issue is that a number of daemons that talk to the cloud can misbehave. Some people have reported success by disabling them. But you can't disable all of them and there's not one set of faulty ones. And they're back after a restart. Again, you need to wait for Apple to fix it.
A third problem lies in the set of adapters used to connect. When you've got a Firewire connection, for instance, you go from USB-C to TB3 to TB2 to FW, to end with a FW800 to FW400 cable, possibly. Some third party adapters don't work for audio. Most docks don't work. Only a few gigabit ethernet adapters work with netboot
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In a time of deceit telling the truth is a revolutionary act.
George Orwell
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