I haven't listened to any Kyuss album in a long time, but I seem to recall they used lots of midrange (peaking around 500k, 100 an1500Kz) and a "spongy" tube distortion (not enough to be considered metal but gritty enough for rock). More in the veins of a heavily pushed and distorted Fender amp.
I will try and rescue my Kyuss CDs from the vaults and think of a more adequate answer.
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