I'd check out Presonus' line of products. They all work great with Reaper, for one, and they've got great support. Preamps are excellent for this price range, and the control software that goes with them is slick.
http://www.presonus.com/products/pro...?ListingType=1
Highly recommended.
- Gizz
P.S. If you like firewire the Firestudio is great and is probably a bit cheaper now that they've released their newer USB systems.