I think that would need testing and might even differ between systems.
FWIW, I suspect that ALSA might have the edge, as reaper then has exclusive access to device, with JACK there might be other clients and there is some code overhead.
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Reaper for Linux Documentation (WIP). Software: Archlinux/KDE, Fabfilter FX, Komplete 8, Nebula, Schwa/Stillwell, T-racks Max/Amplitube/SVX, etc. Gear: i7-2600k/4700HQ/16GB, RME Multiface/Babyface, Behringer X32, Genelec 8040, etc. :)
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