MIDI Keyboard Deploy was written to do this, if I understand your request.
Set up a few tracks for incoming midi, create sends on the midi tracks to the VSTi tracks.
Each Incoming midi track could have a copy of Keyboard Deploy with different splits. Then use some buttons on the MIDI keyboard, mapped to Track Mute in reaper's Preferences\Keyboard Control for activating/deactivating the Incoming MIDI Tracks(each with a different Filter), thereby remapping your keyboard on the fly with a single button press.
Alternately for the Mute Keybinding, you could bind your computer keyboard to Mute/Solo Tracks. Make a special Live template that requires a single key press to Mute/UnMute specific tracks. With 6 layers of commands for each keybinding the combinations of what a single button press could do for Muting/Soloing track selections could be mind boggling with possibilities, or kept very simple.
Lotsa ways to do this, it's just a matter of finding which is best for you.
If you try out Keyboard Deploy, and it doesn't work, or it doesn't make sense, post the complaint in that thread.
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