JS plugins are largely OS-ignorant. Reaper compiles them when you load the plugin on a track. There might be something wrong in the code which will cause a bug that's specific to a particular Reaper on a particular OS, but it would be rare. All the JS plugins I've tried worked fine in Windows, OSX and Linux in the native Reaper versions for each OS.
If you don't specify the plugin (and/or post it for analysis), you probably won't get any help.
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